Prevalence and in vitro antifungal susceptibility of Candida spp isolated from clinical specimens in São Paulo, Brazil.
نویسندگان
چکیده
We examined the prevalence and the in vitro susceptibility to antifungal drugs of Candida spp isolated from clinical specimens at our university hospital in São Paulo, Brazil. Among 6,417 samples studied, positive cultures, were obtained from 222 (3.5%) most of them (68%) from the pediatric unit and nursery. Candida albicans and Candida parapsilosis were the most frequent species and the susceptibility patterns of a panel of 130 isolates to amphotericin B, ketoconazole and fluconazole, showed that the order of antifungal efficacy was amphotericin B > ketoconazole > fluconazole.
منابع مشابه
Epidemiology and antifungal susceptibility of Candida species in a tertiary care hospital, Kolkata, India
Background and Purpose: The incidence of fungal infection as well as candidemia has increased significantly, contributing to morbidity and mortality in the developed countries. The alarming increase in infections with multidrug resistant bacteria is due to overuse of a broad spectrum antimicrobials, which leads to over growth of Candida spp.; thus, enhancing its opportunity to cause the disease...
متن کاملSusceptibility pattern of anti-candida drugs in the pediatric patients with acute leukemia
Background: Pediatric patients on chemotherapy are vulnerable to invasive fungal infection especially Candida spices. Resistance to antifungal agents has increased in Candida spp., especially in non-albicans species. This study aims to assess the susceptibility of Candida spp. strains isolated from children with acute leukemia less than 18 years. Materials and Methods: This prospective cross-s...
متن کاملPrevalence of Fungal Infections in Children with Hematologic Disorders and Determination of Anti-Fungal Susceptibility in Isolated Species
Background & Aims: Fungal infections are among the most common life threatening conditions in patients with hematologic malignancies. The present study was carried out on children hospitalized in Amir Oncology Hospital of Shiraz, Iran, in order to determine the prevalence of fungal infections and respective susceptibility patterns to prophylactic antifungal therapies. Methods: Colonization was ...
متن کاملAntifungal Drug Susceptibility of Candida Species Isolated from HIV-Positive Patients Recruited at a Public Hospital in São Luís, Maranhão, Brazil
Oropharyngeal candidiasis is the most common fungal infection in hospitalized patients with acquired immune deficiency syndrome (AIDS). Its progression results in invasive infections, which are a significant cause of morbidity and mortality. This study aimed to quickly and accurately identify Candida spp. from oral mucosa of AIDS patients recruited at Presidente Vargas Hospital, in São Luís cit...
متن کاملتعیین گونه‌های کاندیدای غیرآلبیکنس از نمونه‌های بالینی بیماران مبتلا به کاندیدیازیس
Background: I Infections due to Candida spp. have increased dramatically in recent years through a rising number of predisposing factors and immunocompromised hosts. Although Candida albicans is the most prevalent and important causative agent of Candida infections, the importance of C. parapsilosis, C. tropicalis, C. krusei, C. glabrata, C. guilliermondii and C. kefyr have increased significan...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Revista iberoamericana de micologia
دوره 15 1 شماره
صفحات -
تاریخ انتشار 1998